作者
Juliana R Caldas, Ronney B Panerai, Edson Bor-Seng-Shu, Graziela SR Ferreira, Ligia Camara, RH Passos, Marcelo de-Lima-Oliveira, Filomena RBG Galas, Juliano P Almeida, Ricardo C Nogueira, Natalia Mian, Fabio A Gaiotto, Thompson G Robinson, Ludhmila A Hajjar
发表日期
2019/1/1
期刊
Clinical Neurophysiology
卷号
130
期号
1
页码范围
101-108
出版商
Elsevier
简介
Objective
We investigated the potential association of cerebral autoregulation (CA) with postoperative delirium (PD), a common complication of cardiac surgery with cardiopulmonary bypass (CPB).
Methods
In patients undergoing coronary artery bypass graft (CABG) surgery with CPB, cerebral blood flow velocity (CBFV) and blood pressure (BP) were continuously recorded during 5-min preoperatively (T1), after 24 h (T2), and 7 days after procedure (T3). Prospective multivariate logistic regression analysis was performed to determine the independent risk factors of PD. Autoregulation index (ARI) was calculated from the CBFV response to a step change in BP derived by transfer function analysis.
Results
In 67 patients, mean age 64.3 ± 9.5 years, CA was depressed at T2 as shown by values of ARI (3.9 ± 1.7), compared to T1 (5.6 ± 1.7) and T3 (5.5 ± 1.8) (p < 0.001). Impaired CA was found in 37 (55 …
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JR Caldas, RB Panerai, E Bor-Seng-Shu, GSR Ferreira… - Clinical Neurophysiology, 2019