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The patient, a 51-year-old woman, had noted the development of orbital signs 1 year before she was diagnosed as having AL amyloidosis. Also known as raccoon’s eyes, this has been described to occur in association with a few diseases, primary amyloidosis and multiple myeloma among them. Raccoon’s eye is a consequence of vascular fragility induced by the deposition of amyloid and is sometimes associated with abnormal clotting, which can also occur in AL amyloidosis (1–3).