作者
Joanne R Campione, Natalie D Ritchie, Howard A Fishbein, Russell E Mardon, Maurice C Johnson Jr, Wilson Pace, Rebecca Jeffries Birch, Eileen L Seeholzer, Xuanping Zhang, Krista Proia, Karen R Siegel, Kai McKeever Bullard
发表日期
2022/10/1
期刊
American journal of preventive medicine
卷号
63
期号
4
页码范围
603-610
出版商
Elsevier
简介
Introduction
RCTs have found that type 2 diabetes can be prevented among high-risk individuals by metformin medication and evidence-based lifestyle change programs. The purpose of this study is to estimate the use of interventions to prevent type 2 diabetes in real-world clinical practice settings and determine the impact on diabetes-related clinical outcomes.
Methods
The analysis performed in 2020 used 2010‒2018 electronic health record data from 69,434 patients aged ≥18 years at high risk for type 2 diabetes in 2 health systems. The use and impact of prescribed metformin, lifestyle change program, bariatric surgery, and combinations of the 3 were examined. A subanalysis was performed to examine uptake and retention among patients referred to the National Diabetes Prevention Program.
Results
Mean HbA1c values declined from before to after intervention for patients who were prescribed metformin (−0 …
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JR Campione, ND Ritchie, HA Fishbein, RE Mardon… - American journal of preventive medicine, 2022