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MR‐guided Laser Induced Thermal Therapy (LITT) is a procedure for intracranial tumors. Minimal data exists regarding post‐procedure lesion volume changes.

We aim to analyze changes in lesion volume during the post‐LITT period using polygonal tracing with fusion. Additionally, we investigated the role of lesion histopathology on LITT parameters and volume dynamics.

Sixteen patients with intracranial neoplasms received LITT. Using OsiriX DICOM Viewer, three raters computed lesion volumes at the following: pre‐ablation (PreA), immediate post‐ablation (IPA), 24 hours post‐ablation (24PA), and first follow‐up post‐ablation (FPA), which ranged from 4 to 11 weeks post‐ablation. Statistical analyses for volume changes between time points and inter‐rater reliability were performed. Additionally, comparisons were made between metastatic versus non‐metastatic and small …