作者
Amani Meaidi, Annamaria Mascolo, Maurizio Sessa, Anne Pernille Toft-Petersen, Regitze Skals, Thomas Alexander Gerds, Charlotte Wessel Skovlund, Lina Steinrud Morch, Francesco Rossi, Annalisa Capuano, Oejvind Lidegaard, Christian Torp-Pedersen
发表日期
2023/9/6
期刊
bmj
卷号
382
出版商
British Medical Journal Publishing Group
简介
Objective
To study the influence of concomitant use of hormonal contraception and non-steroidal anti-inflammatory drugs (NSAIDs) on the risk of venous thromboembolism.
Design
Nationwide cohort study.
Setting
Denmark through national registries.
Participants
All 15-49 year old women living in Denmark between 1996 and 2017 with no medical history of any venous or arterial thrombotic event, cancer, thrombophilia, hysterectomy, bilateral oophorectomy, sterilisation, or infertility treatment (n=2 029 065).
Main outcome measure
A first time discharge diagnosis of lower limb deep venous thrombosis or pulmonary embolism.
Results
Among 2.0 million women followed for 21.0 million person years, 8710 venous thromboembolic events occurred. Compared with non-use of NSAIDs, use of NSAIDs was associated with an adjusted incidence rate ratio of venous thromboembolism of 7.2 (95% confidence interval 6.0 to 8 …
学术搜索中的文章
A Meaidi, A Mascolo, M Sessa, AP Toft-Petersen… - bmj, 2023