作者
Ø Lidegaard
发表日期
1993/4/10
期刊
British Medical Journal
卷号
306
期号
6883
页码范围
956-963
出版商
British Medical Journal Publishing Group
简介
OBJECTIVE
To assess the risk of cerebral thromboembolism in women using low dose oral contraceptives.
DESIGN
A retrospective case-control study.
SETTING
All Danish medical, neurological, neurosurgical, and gynaecological departments.
SUBJECTS
All 794 women in Denmark aged 15-44 who had suffered a cerebral thromboembolic attack during 1985-9 and 1588 age matched randomly selected controls.
RESULTS
Of 692/1584 case/control questionnaires sent out, 590/1396 (85.3%/88.1%) were returned. Among the cases, 15 refused to participate, 69 had a revised or unreliable diagnosis, 40 had had thromboembolic disease previously, 13 were pregnant, and 152 had a disease predisposing to a cerebral thromboembolic attack. Of the 323 cases without a known predisposition, 320 reported use or non-use of oral contraception. Among the 1396 controls, eight refused to participate, were mentally retarded …
引用总数
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