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Methods

This is a prospective registry of all consecutive patients with severe MR which developed early after an acute transmural myocardial infarction who underwent percutaneous mitral valve repair (PMVR) at 11 centres across Europe between January 2016 and December 2018. The main exclusion criterion was low probability of success with the device. Clinical condition did not contraindicate the procedure. Detailed inclusion and exclusion criteria and more information regarding methods are shown in Supplementary Appendix 1.

Results

Between January 2016 and December 2018, 883 cases were treated with the MitraClip in the recruiting centres. Among them, 44 (5%) patients (63.6% male, mean age 70.0±10.8 years) were included in the study. Median time from MI to treatment was 18 days (13-36.8 days) and from diagnosis of MR to treatment 12.5 days (4.5-18 days).