作者
Mikkel Højlund, Lotte Rasmussen, Morten Olesen, Trine Munk‐Olsen, Anton Pottegård
发表日期
2022/9
期刊
British Journal of Clinical Pharmacology
卷号
88
期号
9
页码范围
4224-4229
简介
The second‐generation antipsychotic quetiapine is commonly used off‐label for its anxiolytic and hypnotic properties. However, quetiapine is associated with problematic side‐effects. We used Danish Medicinal Product Statistics and a 20% random sample of the Danish population's prescription fills (2001–2020) to describe the utilization of quetiapine and proportion of various prescriber types (general practitioner [GP], specialist in private practice, hospital physician and other prescribers) both in connection to first‐time and subsequent prescriptions. In 2020, 92% of all quetiapine was dispensed outside hospitals and the average daily dispensed quantity of quetiapine per user corresponded to 100 mg/user/d. A GP issued 53% of first‐time prescriptions and 75% of subsequent prescriptions for quetiapine in 2020. The proportion of quetiapine prescriptions issued by GPs varied by age group—from 14% among 0–17 …
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M Højlund, L Rasmussen, M Olesen, T Munk‐Olsen… - British Journal of Clinical Pharmacology, 2022