作者
Amy Krain Roy, Zarrar Shehzad, Daniel S Margulies, AM Clare Kelly, Lucina Q Uddin, Kristin Gotimer, Bharat B Biswal, F Xavier Castellanos, Michael P Milham
发表日期
2009/4/1
期刊
Neuroimage
卷号
45
期号
2
页码范围
614-626
出版商
Academic Press
简介
The amygdala is composed of structurally and functionally distinct nuclei that contribute to the processing of emotion through interactions with other subcortical and cortical structures. While these circuits have been studied extensively in animals, human neuroimaging investigations of amygdala-based networks have typically considered the amygdala as a single structure, which likely masks contributions of individual amygdala subdivisions. The present study uses resting state functional magnetic resonance imaging (fMRI) to test whether distinct functional connectivity patterns, like those observed in animal studies, can be detected across three amygdala subdivisions: laterobasal, centromedial, and superficial. In a sample of 65 healthy adults, voxelwise regression analyses demonstrated positively-predicted ventral and negatively-predicted dorsal networks associated with the total amygdala, consistent with …
引用总数
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AK Roy, Z Shehzad, DS Margulies, AMC Kelly… - Neuroimage, 2009