作者
Sabeeha S Merchant, Simon E Prochnik, Olivier Vallon, Elizabeth H Harris, Steven J Karpowicz, George B Witman, Astrid Terry, Asaf Salamov, Lillian K Fritz-Laylin, Laurence Maréchal-Drouard, Wallace F Marshall, Liang-Hu Qu, David R Nelson, Anton A Sanderfoot, Martin H Spalding, Vladimir V Kapitonov, Qinghu Ren, Patrick Ferris, Erika Lindquist, Harris Shapiro, Susan M Lucas, Jane Grimwood, Jeremy Schmutz, Pierre Cardol, Heriberto Cerutti, Guillaume Chanfreau, Chun-Long Chen, Valérie Cognat, Martin T Croft, Rachel Dent, Susan Dutcher, Emilio Fernández, Hideya Fukuzawa, David González-Ballester, Diego González-Halphen, Armin Hallmann, Marc Hanikenne, Michael Hippler, William Inwood, Kamel Jabbari, Ming Kalanon, Richard Kuras, Paul A Lefebvre, Stéphane D Lemaire, Alexey V Lobanov, Martin Lohr, Andrea Manuell, Iris Meier, Laurens Mets, Maria Mittag, Telsa Mittelmeier, James V Moroney, Jeffrey Moseley, Carolyn Napoli, Aurora M Nedelcu, Krishna Niyogi, Sergey V Novoselov, Ian T Paulsen, Greg Pazour, Saul Purton, Jean-Philippe Ral, Diego Mauricio Riaño-Pachón, Wayne Riekhof, Linda Rymarquis, Michael Schroda, David Stern, James Umen, Robert Willows, Nedra Wilson, Sara Lana Zimmer, Jens Allmer, Janneke Balk, Katerina Bisova, Chong-Jian Chen, Marek Elias, Karla Gendler, Charles Hauser, Mary Rose Lamb, Heidi Ledford, Joanne C Long, Jun Minagawa, M Dudley Page, Junmin Pan, Wirulda Pootakham, Sanja Roje, Annkatrin Rose, Eric Stahlberg, Aimee M Terauchi, Pinfen Yang, Steven Ball, Chris Bowler, Carol L Dieckmann, Vadim N Gladyshev, Pamela Green, Richard Jorgensen, Stephen Mayfield, Bernd Mueller-Roeber, Sathish Rajamani, Richard T Sayre, Peter Brokstein, Inna Dubchak, David Goodstein, Leila Hornick, Y Wayne Huang, Jinal Jhaveri, Yigong Luo, Diego Martinez, Wing Chi Abby Ngau, Bobby Otillar, Alexander Poliakov, Aaron Porter, Lukasz Szajkowski, Gregory Werner, Kemin Zhou, Igor V Grigoriev, Daniel S Rokhsar, Arthur R Grossman
发表日期
2007/10/12
期刊
Science
卷号
318
期号
5848
页码范围
245-250
出版商
American Association for the Advancement of Science
简介
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the ∼120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.
引用总数
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SS Merchant, SE Prochnik, O Vallon, EH Harris… - Science, 2007