作者
EGA Karssemeijer, WJR Bossers, JA Aaronson, RPC Kessels, MGM Olde Rikkert
发表日期
2017/12
期刊
BMC geriatrics
卷号
17
期号
1
页码范围
73
出版商
BioMed Central
简介
Background
To date there is no cure or an effective disease-modifying drug to treat dementia. Available acetylcholine-esterase inhibiting drugs or memantine only produce small benefits on cognitive and behavioural functioning and their clinical relevance remains controversial. Combined cognitive-aerobic interventions are an appealing alternative or add-on to current pharmacological treatments. The primary aim of this study is to investigate the efficacy of a combined cognitive-aerobic training and a single aerobic training compared to an active control group in older adults with mild dementia. We expect to find a beneficial effect on executive functioning in both training regimes, compared to the control intervention, with the largest effect in the combined cognitive-aerobic group. Secondary, intervention effects on cognitive functioning in other domains, physical functioning, physical activity …
引用总数
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