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Social Media Promotion (SMP) of prescription drugs can be helpful, as it provides us emotional support, it helps marginalized groups of patients to reach out to their physician. But sometimes it might turn into lethal as it can motivate patients for self-medication, it can negatively impact patient-physician relationship. Thus, SMP for prescription drugs is a topic that should be considered critically to study, as the interests of patients is involved. The present study analyzes the impact of social media promotion of prescription medicine among patients of Eastern India. To understand the impact a cross-section study was carried out and a survey was done. Cronbach's α was done to check the reliability of collected data and, ANCOVA was used to determine if there are significant differences in responses. The study shows that number of female students, who are using social media to search the health information in social media, higher than male students in most of the cases. From the study, it is also found that social media promotion of prescription drugs leads to self-medication and patients are also using it to get emotional support. Respondents reported that patients are using social media platforms to get health information, their attitude does not get affected by the users‟ geographical area irrespective of their gender.