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Attempts to address the growing problem of healthcare-associated infections (HAIs) and their impact on healthcare systems have historically relied on infection control policies that recommend good hygiene through standard and enhanced precautions (e.g. barrier precautions and patient isolation). In order for infection control strategies to be effective, however, healthcare workers' behaviour must be congruent with these policies. The purposes of this systematic review were to evaluate studies testing the effectiveness of interventions aimed at changing healthcare workers' behaviour (in reducing HAIs) and to summarize the findings of the studies with the highest quality scores. A total of 33 published studies met the inclusion criteria and were evaluated. Four of these earned a study quality score of ≥80%. In all four significant reductions in HAI or colonization rates were reported. Behavioural interventions used in …