查看文章

A series of diorganotin (IV) complexes of N-(2-hydroxy-1-naphthylidene) glycine (1), having general formula [Me2SnOPri (Hhngl)](2),[Me2Sn (Hhngl) 2](3),[Bu2SnOPri (Hhngl)](4),[Bu2Sn (Hhngl) 2](5),[Ph2Sn (hngl)](6),[Ph2Sn (Hhngl) 2](7),[where H2hngl= N-(2-hydroxy-1-naphthylidene) glycine] were synthesized by reacting of diorganotin (IV) chloride with the ligand, with the aid of sodium iso-propoxide in appropriate stiochiometric ratios (1: 1, 1: 2). All the complexes exhibit good antibacterial activity against two Gram-positive bacteria namely, Staphylococcus aureus, Bacillus subtilis and two Gram-negative bacteria namely, Escherichia coli and Pseudomonas aeruginosa. All the complexes were also exhibit remarkable antifungal activity against three pathogenic fungi namely, Aspergillus niger, A. flavus and Penicillium sp.