作者
Michael G Hart, Ruth Garside, Gabriel Rogers, Margaret Somerville, Ken Stein, Robin Grant, Cochrane Gynaecological, Neuro‐oncology and Orphan Cancer Group
发表日期
1996/9/1
来源
Cochrane Database of Systematic Reviews
卷号
2018
期号
7
出版商
John Wiley & Sons, Ltd
简介
Background
Standard treatment for high grade glioma (HGG) usually entails surgery (either biopsy or resection) followed by radiotherapy plus or minus temozolomide. Implanting wafers impregnated with chemotherapy agents into the resection cavity represents a novel means of delivering drugs directly to the resection cavity with potentially fewer systemic side effects. It is not clear how effective this modality is or whether it should be recommended as part of standard care for patients with HGG.
Objectives
To estimate the clinical effectiveness of chemotherapy wafers for patients with HGG.
Search methods
The following databases were searched: CENTRAL (issue 4. 2010); MEDLINE and EMBASE. The original search strategy also included: Science Citation Index; Physician Data Query; and the meta‐Register of Controlled Trials. Reference lists of all identified studies were searched. The Journal of Neuro …
引用总数
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