作者
Alberto Salvaggio, Gian Enrico Magi, Giacomo Rossi, Adolfo Maria Tambella, Cecilia Vullo, Andrea Marchegiani, Riccardo Botto, Angela Palumbo Piccionello
发表日期
2020/5
期刊
Veterinary Surgery
卷号
49
期号
4
页码范围
719-727
出版商
John Wiley & Sons, Inc.
简介
Objective
To determine the effect of the Klox fluorescence biomodulation system (Phovia) on the healing of surgical wounds.
Study design
Prospective, blinded, controlled clinical trial.
Sample population
Healthy dogs undergoing orthopedic surgery (n = 10).
Methods
Half of the length of each surgical wound was treated with Phovia, and the remaining 50% was treated with saline solution on the first day after surgery and every 3 days until day 13. Wound healing of treated and control areas within each wound was evaluated via macroscopic assessment and histological and immunohistochemical analysis of treated and control wounds.
Results
The areas treated with Phovia achieved lower histology scores (P = .001), consistent with complete re‐epithelialization, less inflammation of the dermal layer, and greater and more regular deposition of collagen. According to immunohistochemistry, expression of factor …
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A Salvaggio, GE Magi, G Rossi, AM Tambella, C Vullo… - Veterinary Surgery, 2020