作者
Güler Burcu Senirkentli, Fatih Ekinci, Erkan Bostanci, Mehmet Serdar Güzel, Özlem Dağli, Ahmad M Karim, Alok Mishra
发表日期
2021/2/4
期刊
Healthcare
卷号
9
期号
2
页码范围
167
出版商
MDPI
简介
Purpose
In this study, the required dose rates for optimal treatment of tumoral tissues when using proton therapy in the treatment of defective tumours seen in mandibles has been calculated. We aimed to protect the surrounding soft and hard tissues from unnecessary radiation as well as to prevent complications of radiation. Bragg curves of therapeutic energized protons for two different mandible (molar and premolar) plate phantoms were computed and compared with similar calculations in the literature. The results were found to be within acceptable deviation values.
Methods
In this study, mandibular tooth plate phantoms were modelled for the molar and premolar areas and then a Monte Carlo simulation was used to calculate the Bragg curve, lateral straggle/range and recoil values of protons remaining in the therapeutic energy ranges. The mass and atomic densities of all the jawbone layers were selected and the effect of layer type and thickness on the Bragg curve, lateral straggle/range and the recoil were investigated. As protons move through different layers of density, lateral straggle and increases in the range were observed. A range of energies was used for the treatment of tumours at different depths in the mandible phantom.
Results
Simulations revealed that as the cortical bone thickness increased, Bragg peak position decreased between 0.47–3.3%. An increase in the number of layers results in a decrease in the Bragg peak position. Finally, as the proton energy increased, the amplitude of the second peak and its effect on Bragg peak position decreased.
Conclusion
These findings should guide the selection of appropriate energy …
引用总数
学术搜索中的文章
GB Senirkentli, F Ekinci, E Bostanci, MS Güzel, Ö Dağli… - Healthcare, 2021