作者
Fen Miao, Yun-Peng Cai, Yu-Xiao Zhang, Ye Li, Yuan-Ting Zhang
发表日期
2015/8/25
期刊
Computational and mathematical methods in medicine
卷号
2015
出版商
Hindawi Publishing Corporation
简介
Existing models for predicting mortality based on traditional Cox proportional hazard approach (CPH) often have low prediction accuracy. This paper aims to develop a clinical risk model with good accuracy for predicting 1‐year mortality in cardiac arrhythmias patients using random survival forest (RSF), a robust approach for survival analysis. 10,488 cardiac arrhythmias patients available in the public MIMIC II clinical database were investigated, with 3,452 deaths occurring within 1‐year followups. Forty risk factors including demographics and clinical and laboratory information and antiarrhythmic agents were analyzed as potential predictors of all‐cause mortality. RSF was adopted to build a comprehensive survival model and a simplified risk model composed of 14 top risk factors. The built comprehensive model achieved a prediction accuracy of 0.81 measured by c‐statistic with 10‐fold cross validation. The …
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