作者
Anna L Wrobel, Samantha E Russell, Anuradhi Jayasinghe, Bianca E Kavanagh, Mojtaba Lotfaliany, Alyna Turner, Olivia M Dean, Sue M Cotton, Claudia Diaz-Byrd, Anastasia K Yocum, Elizabeth R Duval, Tobin J Ehrlich, David F Marshall, Michael Berk, Melvin G McInnis
发表日期
2023/7
期刊
Australian & New Zealand Journal of Psychiatry
卷号
57
期号
7
页码范围
1031-1042
出版商
SAGE Publications
简介
Background
Childhood trauma is negatively associated with depression severity in bipolar disorder; however, the underlying mechanisms remain unclear. We investigated whether personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) mediate the relationship between childhood trauma and the severity of bipolar depression.
Methods
Data from 209 individuals with bipolar disorder recruited for the Prechter Longitudinal Study of Bipolar Disorder were analysed. Using structural equation modelling, we examined the direct and indirect associations between childhood trauma (Childhood Trauma Questionnaire) and depression severity (Hamilton Depression Rating Scale) – with the personality traits (NEO Personality Inventory–Revised) as mediators.
Results
The direct effect of childhood trauma on depression severity (standardised β = 0.32, 95% bootstrap confidence interval [CI] = 0 …
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