作者
Bianca E Kavanagh, Sharon Lee Brennan-Olsen, Alyna Turner, Olivia M Dean, Michael Berk, Melanie M Ashton, Heli Koivumaa-Honkanen, Lana J Williams
发表日期
2019/4/1
来源
BMJ open
卷号
9
期号
4
页码范围
e025145
出版商
British Medical Journal Publishing Group
简介
Introduction
Remission rates for mood disorders, including depressive and bipolar disorders, remain relatively low despite available treatments, and many patients fail to respond adequately to these interventions. Evidence suggests that personality disorder may play a role in poor outcomes. Although personality disorders are common in patients with mood disorders, it remains unknown whether personality disorder affects treatment outcomes in mood disorders. We aim to review currently available evidence regarding the role of personality disorder on pharmacological interventions in randomised controlled trials for adults with mood disorders.
Methods and analysis
A systematic search of Cochrane Central Register of Controlled Clinical Trials (CENTRAL) via cochranelibrary.com, PubMed via PubMed, EMBASE via embase.com, PsycINFO via Ebsco and CINAHL Complete via Ebsco databases will be conducted to …
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BE Kavanagh, SL Brennan-Olsen, A Turner, OM Dean… - BMJ open, 2019