作者
Birsen Doganay, Sercan Okutucu, Mustafa Cetin, Emrullah Kızıltunc, Orhan Karayigit, Can Ozkan, Muhammed Fevzi Kılınckaya, Ender Ornek
发表日期
2019/7
期刊
Acta Cardiologica Sinica
卷号
35
期号
4
页码范围
360
出版商
Taiwan Society of Cardiology
简介
Background
Copeptin is widely used as a predictor of an adverse prognosis in many clinical conditions. Reduced antegrade coronary flow in an infarct-related artery (IRA) is associated with adverse clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to investigate whether copeptin level on admission was associated with IRA patency in STEMI patients.
Methods
A total of 88 patients were enrolled into the study and divided into two groups according to TIMI flow grade in the IRA before primary percutaneous coronary intervention.
Results
White blood cell count (p= 0.015), neutrophils (p= 0.047), N-terminal pro-brain natriuretic peptide (NTproBNP)(p< 0.001), copeptin (p< 0.001) and peak troponin I (p= 0.001) were significantly higher in the occluded IRA group with a significantly lower serum sodium level (p< 0.001). Age-and gender-adjusted multivariate …
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B Doganay, S Okutucu, M Cetin, E Kızıltunc, O Karayigit… - Acta Cardiologica Sinica, 2019