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Background

Neuropsychiatric symptoms (NPS) may be prevalent in patients with mild cognitive impairment (MCI). However, little studies compare NPS of MCI between Taiwanese and Western samples.

Methods

This was a cross-sectional study. A total of 268 participants were recruited from the outpatient clinics of two hospitals in Northern Taiwan from 2007–2011. A total of 249 participants completed the cognitive and neuropsychiatric evaluations, including 90 normal controls (NC) and 159 MCI subjects. The MCI criteria followed Petersen criteria except with more stringent requirement that the neurocognitive impairment had to be 4% below mean of norm. The Neuropsychiatric Inventory (NPI) was used to assess the NPS. The prevalence of each neuropsychiatric symptoms was compared between our study and previous studies.

Results

The prevalence of at least one NPS in MCI group was 54.7%. Four of the most …