作者
Kimberley A Lewis, Dipayan Chaudhuri, Gordon Guyatt, Karen EA Burns, Karen Bosma, Long Ge, Tim Karachi, Thomas Piraino, Shannon M Fernando, Nischal Ranganath, Laurent Brochard, Bram Rochwerg
发表日期
2019/9/1
来源
BMJ open
卷号
9
期号
9
页码范围
e030407
出版商
British Medical Journal Publishing Group
简介
Introduction
Timely liberation from invasive mechanical ventilation is important to reduce the risk of ventilator-associated complications. Once a patient is deemed ready to tolerate a mode of partial ventilator assist, clinicians can use one of multiple ventilatory modes. Despite multiple trials, controversy regarding the optimal ventilator mode to facilitate liberation remains. Herein, we report the protocol for a systematic review and network meta-analysis comparing modes of ventilation to facilitate the liberation of a patient from invasive mechanical ventilation.
Methods and analysis
We will search MEDLINE, EMBASE, PubMed, the Cochrane Library from inception to April 2019 for randomised trials that report on critically ill adults who have undergone invasive mechanical ventilation for at least 24 hours and have received any mode of assisted invasive mechanical ventilation compared with an alternative mode of assisted …
学术搜索中的文章
KA Lewis, D Chaudhuri, G Guyatt, KEA Burns, K Bosma… - BMJ open, 2019