作者
Ron J Keizer, Rob Ter Heine, Adam Frymoyer, Lawrence J Lesko, Ranvir Mangat, Srijib Goswami
发表日期
2018/12
来源
CPT: pharmacometrics & systems pharmacology
卷号
7
期号
12
页码范围
785-787
简介
The development of model‐informed precision dosing (MIPD) tools, especially in the form of native or web‐based applications to be used at the bedside, has garnered marked attention in recent years. Their potential clinical benefit can be large, but it should be ensured that such tools make optimal use of available clinical data and have adequate predictive ability. Unique scientific challenges specific to MIPD remain, which may require adaptation of commonly used diagnostics in pharmacometrics.
引用总数
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RJ Keizer, R Ter Heine, A Frymoyer, LJ Lesko… - CPT: pharmacometrics & systems pharmacology, 2018