作者
Nola M Hylton, Jeffrey D Blume, Wanda K Bernreuter, Etta D Pisano, Mark A Rosen, Elizabeth A Morris, Paul T Weatherall, Constance D Lehman, Gillian M Newstead, Sandra Polin, Helga S Marques, Laura J Esserman, Mitchell D Schnall
发表日期
2012/6
期刊
Radiology
卷号
263
期号
3
页码范围
663-672
出版商
Radiological Society of North America, Inc.
简介
Purpose
To compare magnetic resonance (MR) imaging findings and clinical assessment for prediction of pathologic response to neoadjuvant chemotherapy (NACT) in patients with stage II or III breast cancer.
Materials and Methods
The HIPAA-compliant protocol and the informed consent process were approved by the American College of Radiology Institutional Review Board and local-site institutional review boards. Women with invasive breast cancer of 3 cm or greater undergoing NACT with an anthracycline-based regimen, with or without a taxane, were enrolled between May 2002 and March 2006. MR imaging was performed before NACT (first examination), after one cycle of anthracyline-based treatment (second examination), between the anthracycline-based regimen and taxane (third examination), and after all chemotherapy and prior to surgery (fourth examination). MR imaging assessment included …
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