作者
Constance D Lehman, Jeffrey D Blume, Paul Weatherall, David Thickman, Nola Hylton, Ellen Warner, Etta Pisano, Stuart J Schnitt, Constantine Gatsonis, Mitchell Schnall, International Breast MRI Consortium Working Group
发表日期
2005/5/1
期刊
Cancer
卷号
103
期号
9
页码范围
1898-1905
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
BACKGROUND
The authors compared the performance of screening mammography versus magnetic resonance imaging (MRI) in women at genetically high risk for breast cancer.
METHODS
The authors conducted an international prospective study of screening mammography and MRI in asymptomatic, genetically high‐risk women age ≥ 25 years. Women with a history of breast cancer were eligible for a contralateral screening if they had been diagnosed within 5 years or a bilateral screening if they had been diagnosed > 5 years previously. All examinations (MRI, mammography, and clinical breast examination [CBE]) were performed within 90 days of each other.
RESULTS
In total, 390 eligible women were enrolled by 13 sites, and 367 women completed all study examinations. Imaging evaluations recommended 38 biopsies, and 27 biopsies were performed, resulting in 4 cancers diagnosed for an overall 1 …
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