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To compare potential of four types of stem cell in tissue engineering and regenerative medicine applications, osteogenic capacity of newly introduced mesenchymal stem cells (MSCs) derived from buccal fat pads (BFP) (an adipose‐encapsulated mass of the oral cavity), was compared to those isolated from bone marrow (BM‐MSCs), adipose tissue (AT‐MSCs) and unrestricted somatic stem cells (USSCs). Cells were cultured on poly (l‐lactide) (PLLA) nanofibres, Bio‐Oss^®‐coated PLLA (PLLA‐Bio), and culture plates (TCPS) as control.

Capacity of proliferation and osteogenic differentiation of the stem cells was investigated by MTT assay and common osteogenic markers, alkaline phosphatase activity, calcium mineral deposition and bone‐related genes.

Highest proliferation level was observed in cells cultured on PLLA‐Bio, but with no significant difference between …