作者
Carla Roque, Nicola Trevisi, John Silberbauer, Teresa Oloriz, Hiroya Mizuno, Francesca Baratto, Caterina Bisceglia, Nicoleta Sora, Alessandra Marzi, Andrea Radinovic, Fabrizio Guarracini, Pasquale Vergara, Simone Sala, Gabriele Paglino, Simone Gulletta, Patrizio Mazzone, Manuela Cireddu, Giuseppe Maccabelli, Paolo Della Bella
发表日期
2014/12
期刊
Circulation: Arrhythmia and Electrophysiology
卷号
7
期号
6
页码范围
1064-1069
出版商
Lippincott Williams & Wilkins
简介
Background
The mechanism of cardiac resynchronization therapy (CRT)–induced proarrhythmia remains unknown. We postulated that pacing from a left ventricular (LV) lead positioned on epicardial scar can facilitate re-entrant ventricular tachycardia. The aim of this study was to investigate the relationship between CRT-induced proarrhythmia and LV lead location within scar.
Methods and Results
Twenty-eight epicardial and 63 endocardial maps, obtained from 64 CRT patients undergoing ventricular tachycardia ablation, were analyzed. A positive LV lead/scar relationship, defined as a lead tip positioned on scar/border zone, was determined by overlaying fluoroscopic projections with LV electroanatomical maps. CRT-induced proarrhythmia occurred in 8 patients (12.5%). They all presented early with electrical storm (100% versus 39% of patients with no proarrhythmia; P<0.01), requiring temporary biventricular …
学术搜索中的文章
C Roque, N Trevisi, J Silberbauer, T Oloriz, H Mizuno… - Circulation: Arrhythmia and Electrophysiology, 2014