作者
Anders Wallin, Elisabeth Kapaki, Marina Boban, Sebastian Engelborghs, Dirk Matthias Hermann, Branko Huisa, Michael Jonsson, MG Kramberger, Laura Lossi, B Malojcic, Shima Mehrabian, Adalberto Merighi, Elizabeta Blagoja Mukaetova-Ladinska, George P Paraskevas, Bogdan Ovidiu Popescu, Rivka Ravid, Latchezar Traykov, Georgios Tsivgoulis, Galit Weinstein, Amos Korczyn, Maria Bjerke, Gary Rosenberg
发表日期
2017/12
来源
BMC neurology
卷号
17
页码范围
1-12
出版商
BioMed Central
简介
Background
Vascular cognitive impairment (VCI) is a heterogeneous entity with multiple aetiologies, all linked to underlying vascular disease. Among these, VCI related to subcortical small vessel disease (SSVD) is emerging as a major homogeneous subtype. Its progressive course raises the need for biomarker identification and/or development for adequate therapeutic interventions to be tested. In order to shed light in the current status on biochemical markers for VCI-SSVD, experts in field reviewed the recent evidence and literature data.
Method
The group conducted a comprehensive search on Medline, PubMed and Embase databases for studies published until 15.01.2017. The proposal on current status of biochemical markers in VCI-SSVD was reviewed by all co-authors and the draft was repeatedly circulated and discussed before it was finalized …
引用总数
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