作者
Bahiddin Yilmaz, Dilek Erdem, Fatih Teker, Ibrahim Goren, Beytullah Yildirim, Engin Kut, Derya Sarikaya, Memis H Atay, Idris Yucel
发表日期
2016/6
期刊
Journal of International Medical Research
卷号
44
期号
3
页码范围
627-638
出版商
SAGE Publications
简介
Objective
To investigate the effect of immunosuppressive anticancer therapy on titre levels of anti-hepatitis B surface antibodies (anti-HBs) in hepatitis B surface antigen (HBsAg) negative and anti-HBs positive patients with haematological malignancies or solid tumours.
Methods
This retrospective study reviewed the medical records of patients with haematological malignancies or solid tumours. Pretreatment HBsAg negative and anti-HBs positive patients were included in the analysis. Anti-hepatitis B core antibody status was used to evaluate vaccinated patients and those with resolved HBV infections.
Results
The medical records of 237 patients were reviewed retrospectively. The median anti-HBs titre decreased significantly after anticancer therapy compared with the pretreatment median anti-HBs titre in all patients (71 mIU/ml versus 57 mIU/ml). Anti-HBs titre decreased significantly in patients with haematological …
学术搜索中的文章
B Yilmaz, D Erdem, F Teker, I Goren, B Yildirim, E Kut… - Journal of International Medical Research, 2016