作者
Dhammika Leshan Wannigama, Mohan Amarasiri, Phatthranit Phattharapornjaroen, Cameron Hurst, Charin Modchang, Sudarat Chadsuthi, Suparinthon Anupong, Kazuhiko Miyanaga, Longzhu Cui, Stefan Fernandez, Angkana T Huang, Puey Ounjai, Andrew C Singer, Naveen Kumar Devanga Ragupathi, Daisuke Sano, Takashi Furukawa, Kazunari Sei, Asada Leelahavanichkul, Talerngsak Kanjanabuch, Tanittha Chatsuwan, Paul G Higgins, Asuka Nanbo, Anthony Kicic, Richard Siow, Sam Trowsdale, Parichart Hongsing, Aisha Khatib, Kenji Shibuya, Shuichi Abe, Hitoshi Ishikawa, Wanwara Thuptiang, Ali Hosseini Rad SM, Porames Vatanaprasan, Dylan John Jay, Thammakorn Saethang, Sirirat Luk-in, Robin James Storer, Phitsanuruk Kanthawee, Ratana Tacharoenmuang
发表日期
2024/6/1
期刊
The Lancet Infectious Diseases
卷号
24
期号
6
页码范围
e348-e350
出版商
Elsevier
简介
The SARS-CoV-2 variant JN. 1 swiftly became the global dominant strain1, 2 due to a spike protein Leu455Ser substitution, boosting transmissibility and immune-escape capabilities, surpassing its predecessor BA. 2.86 and other variants. 1, 3, 4 These alterations have resulted in a surge of COVID-19 cases, reflected in wastewatersurveillance data surpassing rates, observed during the initial omicron wave. However, concerns persist that JN. 1 might have an increased capacity to replicate in the gut, potentially leading to infected individuals shedding a higher number of viral copies than previously seen. As there is currently a lack of available data for fecal viral shedding, we are presenting the initial longitudinal and quantitative faecal shedding data for SARS-CoV-2 RNA in individuals infected with XBB. 1.5, EG. 5.1, HV. 1, JD. 1.1, BA. 2.86, and JN. 1. 856 faecal samples were obtained from 113 non-hospitalised …
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DL Wannigama, M Amarasiri, P Phattharapornjaroen… - The Lancet Infectious Diseases, 2024