作者
Kevin B Wilkins, Jun Yao, Meriel Owen, Haleh Karbasforoushan, Carolina Carmona, Julius PA Dewald
发表日期
2020/6
期刊
The Journal of physiology
卷号
598
期号
11
页码范围
2153-2167
简介
Key points
- Ipsilateral‐projecting corticobulbar pathways, originating primarily from secondary motor areas, innervate the proximal and even distal portions, although they branch more extensively at the spinal cord.
- It is currently unclear to what extent these ipsilateral secondary motor areas and subsequent cortical projections may contribute to hand function following stroke‐induced damage to one hemisphere.
- In the present study, we provide both structural and functional evidence indicating that individuals increasingly rely on ipsilateral secondary motor areas, although at the detriment of hand function.
- Increased activity in ipsilateral secondary motor areas was associated with increased involuntary coupling between shoulder abduction and finger flexion, most probably as a result of the low resolution of these pathways, making it increasingly difficult to open the hand.
- These findings suggest that, although …
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KB Wilkins, J Yao, M Owen, H Karbasforoushan… - The Journal of physiology, 2020