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In the last few decades, there has been a surge in the hazardous chemicals contamination in the water bodies in various parts of India. Consequently, bioremediation of these hazardous chemicals by microorganisms has emerged as a lucrative option. Furthermore, advancement in the various physicochemical and robust molecular techniques such as 1D-SDS-PAGE followed by LC-MS/MS analysis as well as metabolite identification by ¹H-NMR has shed light on the various cellular strategies adopted by a microorganism for remediation of a cocktail of metals and pesticide that were either poorly highlighted or unexplained.

With this background the present chapter aims to understand the complete process of a metal or cocktail of multimetal and pesticide mixture remediation by microorganisms such as bacteria, fungus or algae at molecular level by proteomic and metabolomic techniques. Further the scale up of this …