作者
Samantha F Butts, Carter Owen, Monica Mainigi, Suneeta Senapati, David B Seifer, Anuja Dokras
发表日期
2014/10/1
期刊
Fertility and sterility
卷号
102
期号
4
页码范围
1041-1047. e1
出版商
Elsevier
简介
Objective
To investigate the impact of intracytoplasmic sperm injection (ICSI) and assisted hatching (AH) on assisted reproductive technology (ART) outcomes in initial cycles with diminished ovarian reserve (DOR) as the primary diagnosis.
Design
Retrospective cohort study of cycles from the Society for Assisted Reproductive Technology (SART) Clinic Outcome Reporting System database.
Setting
Not applicable.
Patient(s)
A total of 422,949 fresh, nondonor, initial ART cycles of which 8,597 were diagnosed with only elevated FSH and 38,926 were diagnosed with only DOR according to the SART DOR categorization.
Intervention(s)
None.
Main Outcome Measure(s)
Live birth and clinical pregnancy rates.
Result(s)
ICSI and AH were associated with diminished odds of live birth in SART DOR–only cycles (adjusted odds ratio [AOR] 0.88, 95% confidence interval [CI] 0.81–0.96 for ICSI; AOR 0.77, 95% CI 0.71–0.84 for AH …
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