作者
Eddy Fan, Fern Cheek, Linda Chlan, Rik Gosselink, Nicholas Hart, Margaret S Herridge, Ramona O Hopkins, Catherine L Hough, John P Kress, Nicola Latronico, Marc Moss, Dale M Needham, Mark M Rich, Robert D Stevens, Kevin C Wilson, Chris Winkelman, Doug W Zochodne, Naeem A Ali
发表日期
2014/12/15
期刊
American journal of respiratory and critical care medicine
卷号
190
期号
12
页码范围
1437-1446
出版商
American Thoracic Society
简介
Rationale: Profound muscle weakness during and after critical illness is termed intensive care unit–acquired weakness (ICUAW).
Objectives: To develop diagnostic recommendations for ICUAW.
Methods: A multidisciplinary expert committee generated diagnostic questions. A systematic review was performed, and recommendations were developed using the Grading, Recommendations, Assessment, Development, and Evaluation (GRADE) approach.
Measurement and Main Results: Severe sepsis, difficult ventilator liberation, and prolonged mechanical ventilation are associated with ICUAW. Physical rehabilitation improves outcomes in heterogeneous populations of ICU patients. Because it may not be feasible to provide universal physical rehabilitation, an alternative approach is to identify patients most likely to benefit. Patients with ICUAW may be such a group. Our review identified only one case series of …
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