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We compared plasma biomarkers of antioxidant status, oxidative stress, inflammation, and risk for coronary heart disease in long-term vegetarians and age- and sex-matched omnivores.

Thirty vegetarians (mean age ± standard deviation: 44.2 ± 9.0 y) were recruited. The subjects had been vegetarian for 5 to 55 y (21.8 ± 12.2 y). The control group comprised 30 adults selected by age-stratified sampling from a community health project (mean age: 44.0 ± 9.2 y). Fasting plasma total antioxidant status (ferric-reducing antioxidant power), ascorbic acid (AA), α-tocopherol (total and lipid standardized), malondialdehyde, total cholesterol, triacylglycerol, uric acid (UA), and high-sensitivity C-reactive protein (hsCRP) were measured.

Plasma AA was significantly higher in the vegetarians than in the omnivores (90.5 ± 21.0 and 61.8 ± 17.0 μM; P < 0.001). The vegetarians had lower …