作者
Qingxue Sun, Matthias Barz, Bruno G De Geest, Mustafa Diken, Wim E Hennink, Fabian Kiessling, Twan Lammers, Yang Shi
发表日期
2019
来源
Chemical Society Reviews
卷号
48
期号
1
页码范围
351-381
出版商
Royal Society of Chemistry
简介
Immunotherapy is revolutionizing the treatment of cancer. It can achieve unprecedented responses in advanced-stage patients, including complete cures and long-term survival. However, immunotherapy also has limitations, such as its relatively low response rates and the development of severe side effects. These drawbacks are gradually being overcome by improving our understanding of the immune system, as well as by establishing combination regimens in which immunotherapy is combined with other treatment modalities. In addition to this, in recent years, progress made in chemistry, nanotechnology and materials science has started to impact immuno-oncology, resulting in more effective and less toxic immunotherapy interventions. In this context, multiple different nanomedicine formulations and macroscale materials have been shown to be able to boost anti-cancer immunity and the efficacy of …
引用总数
201920202021202220232024193138261010
学术搜索中的文章
Q Sun, M Barz, BG De Geest, M Diken, WE Hennink… - Chemical Society Reviews, 2019