作者
Ping G Tepper, John F Randolph Jr, Daniel S McConnell, Sybil L Crawford, Samar R El Khoudary, Hadine Joffe, Ellen B Gold, Huiyong Zheng, Joyce T Bromberger, Kim Sutton-Tyrrell
发表日期
2012/8/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
97
期号
8
页码范围
2872-2880
出版商
Oxford University Press
简介
Context
Variability in the pattern of change in estradiol (E2) and FSH levels over the menopause transition has not been well defined.
Objective
The current study aimed to determine whether different trajectories of E2 and FSH could be identified and whether race/ethnicity and body mass index were related to the different trajectories.
Design
The Study of Women's Health Across the Nation is a longitudinal observational study of the menopausal transition.
Setting
Women aged 42–52 yr from seven participating sites were recruited and underwent up to 11 annual visits.
Participants
Postmenopausal women with 12 or more months of amenorrhea that was not due to hysterectomy/oophorectomy and who were not using hormone therapy before the final menstrual period participated in the study.
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