作者
Jing-Syuan Huang, Fu-Chi Yang, Wu-Chien Chien, Ta-Chuan Yeh, Chi-Hsiang Chung, Chia-Kuang Tsai, Shih-Jen Tsai, Sung-Sen Yang, Nian-Shen Tzeng, Mu-Hong Chen, Chih-Sung Liang
发表日期
2021/2/1
期刊
JAMA pediatrics
卷号
175
期号
2
页码范围
e205371-e205371
出版商
American Medical Association
简介
Importance
The risk of substance use disorder (SUD) in patients with autism spectrum disorder (ASD) remains unclear.
Objective
To investigate the risk of SUD in patients with ASD and its associations with comorbidities, psychotropic agents (PAs), and mortality.
Design, Setting, and Participants
This retrospective, population-based, cohort study of 1 936 512 participants used data from the Taiwan National Health Insurance Research Database and was conducted from January 1, 2000, to December 31, 2015. Included participants attended at least 3 outpatient visits within the 1-year study period for symptomatic ASD as determined by theInternational Classification of Diseases, Ninth Revision, Clinical Modification(ICD-9-CM) diagnostic codes. Individuals diagnosed with ASD before 2000, those diagnosed with SUD before the first visit for ASD, and those with missing data were excluded from the analysis. Patients with …
引用总数