查看文章

Vocal communication signals can provide listeners with information about the signaler and elicit motivated responses. Auditory cortical and mesolimbic reward circuits are often considered to have distinct roles in these processes, with auditory cortical circuits responsible for detecting and discriminating sounds and mesolimbic circuits responsible for ascribing salience and modulating preference for those sounds. Here, we investigated whether dopamine within auditory cortical circuits themselves can shape the incentive salience of a vocal signal. Female zebra finches demonstrate natural preferences for vocal signals produced by males ("songs"), and we found that brief pairing of passive song playback with pharmacological dopamine manipulations in the secondary auditory cortex significantly altered song preferences. In particular, pairing passive song playback with retrodialysis of dopamine agonists into the …