作者
Jürgen Floege, Joseph Kim, Elizabeth Ireland, Charles Chazot, Tilman Drueke, Angel de Francisco, Florian Kronenberg, Daniele Marcelli, Jutta Passlick-Deetjen, Guntram Schernthaner, Bruno Fouqueray, David C Wheeler, ARO Investigators
发表日期
2011/6/1
期刊
Nephrology Dialysis Transplantation
卷号
26
期号
6
页码范围
1948-1955
出版商
Oxford University Press
简介
Background. A number of US observational studies reported an increased mortality risk with higher intact parathyroid hormone (iPTH), calcium and/or phosphate. The existence of such a link in a European haemodialysis population was explored as part of the Analysing Data, Recognising Excellence and Optimising Outcomes (ARO) Chronic Kidney Disease (CKD) Research Initiative.
Methods. The association between the markers of mineral and bone disease and clinical outcomes was examined in 7970 patients treated in European Fresenius Medical Care facilities over a median of 21 months. Baseline and time-dependent (TD) Cox regression were performed using Kidney Disease Outcomes Quality Initiative (KDOQI) target ranges as reference categories, adjusting for demographics, medical history, dialysis parameters, inflammation, medications and laboratory parameters. Fractional …
引用总数
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