作者
Rimona S Weil, Anette E Schrag, Jason D Warren, Sebastian J Crutch, Andrew J Lees, Huw R Morris
发表日期
2016/11/1
来源
Brain
卷号
139
期号
11
页码范围
2827-2843
出版商
Oxford University Press
简介
Patients with Parkinson’s disease have a number of specific visual disturbances. These include changes in colour vision and contrast sensitivity and difficulties with complex visual tasks such as mental rotation and emotion recognition. We review changes in visual function at each stage of visual processing from retinal deficits, including contrast sensitivity and colour vision deficits to higher cortical processing impairments such as object and motion processing and neglect. We consider changes in visual function in patients with common Parkinson’s disease-associated genetic mutations including GBA and LRRK2. We discuss the association between visual deficits and clinical features of Parkinson’s disease such as rapid eye movement sleep behavioural disorder and the postural instability and gait disorder phenotype. We review the link between abnormal visual function and visual hallucinations, considering …
引用总数
20162017201820192020202120222023202422939515974655946
学术搜索中的文章
RS Weil, AE Schrag, JD Warren, SJ Crutch, AJ Lees… - Brain, 2016