作者
Eun Young Kim, Ju Eun Lim, Ji Ye Jung, Ji Young Son, Kyung Jong Lee, Yoe Wun Yoon, Byung Hoon Park, Jin Wook Moon, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Young Ae Kang
发表日期
2009/12
期刊
BMC infectious diseases
卷号
9
页码范围
1-8
出版商
BioMed Central
简介
Background
Interferon-γ release assay (IGRA) may improve diagnostic accuracy for latent tuberculosis infection (LTBI). This study compared the performance of the tuberculin skin test (TST) with that of IGRA for the diagnosis of LTBI in immunocompromised patients in an intermediate TB burden country where BCG vaccination is mandatory.
Methods
We conducted a retrospective observational study of patients given the TST and an IGRA, the QuantiFERON-TB Gold In-Tube (QFT-IT), at Severance Hospital, a tertiary hospital in South Korea, from December 2006 to May 2009.
Results
Of 211 patients who underwent TST and QFT-IT testing, 117 (55%) were classified as immunocompromised. Significantly fewer immunocompromised than immunocompetent patients had positive TST results (10.3% vs. 27.7%, p 0.001 …
学术搜索中的文章
EY Kim, JE Lim, JY Jung, JY Son, KJ Lee, YW Yoon… - BMC infectious diseases, 2009