作者
So Young Park, Hyun Jung Kim, Kwan Ha Yoo, Yong Bum Park, Seo Woo Kim, Seok Jeong Lee, Eun Kyung Kim, Jung Hyun Kim, Yee Hyung Kim, Ji-yong Moon, Kyung Hoon Min, Sung Soo Park, Jinwoo Lee, Chang-Hoon Lee, Jinkyeong Park, Min Kwang Byun, Sei Won Lee, ChinKook Rlee, Ji Ye Jung, Yun Su Sim
发表日期
2015/3
期刊
Journal of thoracic disease
卷号
7
期号
3
页码范围
356
出版商
AME Publications
简介
Background
Prone positioning for acute respiratory distress syndrome (ARDS) has no impact on mortality despite significant improvements in oxygenation. However, a recent trial demonstrated reduced mortality rates in the prone position for severe ARDS. We evaluated effects of prone position duration and protective lung strategies on mortality rates in ARDS.
Methods
We extensively searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials to identify randomized controlled trials (RCTs) reporting on prone positioning during acute respiratory failure in adults for inclusion in our meta-analysis.
Results
Eight trials met our inclusion criteria, Totals of 1,099 and 1,042 patients were randomized to the prone and supine ventilation positions. The mortality rates associated with the prone and supine positions were 41% and 47%[risk ratio (RR), 0.90; 95% confidence interval (CI), 0.82-0.98, P= 0.02 …
学术搜索中的文章
SY Park, HJ Kim, KH Yoo, YB Park, SW Kim, SJ Lee… - Journal of thoracic disease, 2015