作者
Myrna S. Santos, J. A. P. Gomes, Ana Luisa Hofling-Lima, Luiz V. Rizzo, André C. Romano, Rubens . Belfort Jr.
发表日期
2005
期刊
American Journal of Ophthalmology
卷号
140
简介
PURPOSE
To evaluate the survival of conjunctival limbal grafts and amniotic membrane transplantation (AMT) for total limbal stem cell deficiency (LSCD) and the influence of several parameters as cause of LSCD, dry eye, keratinization, eyelid abnormalities, HLA compatibility, systemic immunosuppression, and keratoplasty (PKP) on surgical outcome.
DESIGN
Prospective, noncomparative, interventional case series.
METHODS
Thirty-three eyes of 31 patients with total LSCD that underwent conjunctival limbal grafts and AMT at the Department of Ophthalmology, Federal University of São Paulo were included in this study. Cumulative graft survival as well as the influence of several variables on surgical outcome was analyzed.
RESULTS
Ten eyes (30%) underwent conjunctival limbal autograft and 23 (70%) underwent conjunctival limbal allograft from living HLA-matched donor. Graft survival was seen in 13 eyes …
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