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Studies describing the use of essential oil constituents as antimicrobial agents have steadily increased; however, some phyto‐constituents are often overlooked due to unfavourable minimum inhibitory concentration (MIC) values. Virulence depends on transcriptional factors which are regulated by cell‐to‐cell communication called quorum sensing (QS). This study was undertaken to evaluate the antimicrobial and anti‐QS properties of 29 compounds commonly found in essential oils using two bioreporter strains. QS‐inhibitory activity was assessed qualitatively by agar diffusion and quantitatively by spectrophotometric assays. MICs of all the tested compounds ranged from 0·032 to >5 mg ml⁻¹. Twenty‐two compounds displayed varying levels of QS inhibitory activity with zones of violacein inhibition ranging from 9 to 16 mm. Majority of tested molecules inhibited violacein and pyocyanin production in …