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Our objective was to compare the diagnostic accuracy between the HAS‐BLED score and any of HEMORR₂HAGES, ATRIA, CHADS₂, or CHA₂DS₂‐VASc scores in anticoagulated patients with atrial fibrillation. We systematically searched the Cochrane Library, MEDLINE, PubMed, and Embase databases for relevant studies. Data were extracted and analyzed according to predefined clinical endpoints. Eleven studies were identified. Discrimination analysis demonstrates that HAS‐BLED has no significant C‐statistic differences for bleeding risk prediction compared with ATRIA or HEMORR₂HAGES, but it has significant differences compared with CHADS₂ or CHA₂DS₂‐VASc. The significant positive net reclassification improvement and integrated discrimination improvement values also show that HAS‐BLED is superior to that of any of HEMORR₂HAGES, ATRIA, CHADS₂, or CHA₂DS₂‐VASc scores. According to …