作者
Massimo Iavarone, Roberta D'Ambrosio, Alessandro Soria, Michela Triolo, Nicola Pugliese, Paolo Del Poggio, Giovanni Perricone, Sara Massironi, Angiola Spinetti, Elisabetta Buscarini, Mauro Viganò, Canio Carriero, Stefano Fagiuoli, Alessio Aghemo, Luca S Belli, Martina Luca, Marianna Pedaci, Alessandro Rimondi, Maria Grazia Rumi, Pietro Invernizzi, Paolo Bonfanti, Pietro Lampertico
发表日期
2020/11/1
期刊
Journal of hepatology
卷号
73
期号
5
页码范围
1063-1071
出版商
Elsevier
简介
Background & Aims
Coronavirus disease 2019 (COVID-19) poses a major health threat to healthy individuals and those with comorbidities, but its impact on patients with cirrhosis is currently unknown. Herein, we aimed to evaluate the impact of COVID-19 on the clinical outcome of patients with cirrhosis.
Methods
In this multicentre retrospective study, patients with cirrhosis and a confirmed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection were enrolled between 1st and 31th March 2020. Clinical and biochemical data at diagnosis of COVID-19 and at the last outpatient visit were obtained through review of medical records.
Results
Fifty patients with cirrhosis and confirmed SARS-CoV-2 infection were enrolled (age 67 years, 70% men, 38% virus-related, 52% previously compensated cirrhosis). At diagnosis, 64% of patients presented fever, 42% shortness of breath/polypnea, 22 …
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