作者
Alan Kastner, Kelsey V Stuart, Giovanni Montesano, C Gustavo De Moraes, Jae H Kang, Janey L Wiggs, Louis R Pasquale, Pirro Hysi, Sharon YL Chua, Praveen J Patel, Paul J Foster, Peng T Khaw, Anthony P Khawaja, UK Biobank Eye, Naomi Allen, Tariq Aslam, Denize Atan, Konstantinos Balaskas, Sarah Barman, Jenny Barrett, Paul Bishop, Graeme Black, Tasanee Braithwaite, Roxana Carare, Usha Chakravarthy, Michelle Chan, Sharon Chua, Alexander Day, Parul Desai, Bal Dhillon, Andrew Dick, Alexander Doney, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John Gallacher, David Garway-Heath, Jane Gibson, Jeremy Guggenheim, Chris Hammond, Alison Hardcastle, Simon Harding, Ruth Hogg, Pearse Keane, Peng Khaw, Anthony Khawaja, Gerassimos Lascaratos, Thomas Littlejohns, Andrew Lotery, Robert Luben, Phil Luthert, Tom MacGillivray, Sarah Mackie, Savita Madhusudhan, Bernadette McGuinness, Gareth McKay, Martin McKibbin, Tony Moore, James Morgan, Eoin O'Sullivan, Richard Oram, Chris Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Nikolas Pontikos, Jugnoo Rahi, Alicja Rudnicka, Naveed Sattar, Jay Self, Panagiotis Sergouniotis, Sobha Sivaprasad, David Steel, Irene Stratton, Nicholas Strouthidis, Cathie Sudlow, Zihan Sun, Robyn Tapp, Dhanes Thomas, Emanuele Trucco, Adnan Tufail, Ananth Viswanathan, Veronique Vitart, Mike Weedon, Katie Williams, Cathy Williams, Jayne Woodside, Max Yates, Yalin Zheng, Vision Consortium
发表日期
2023/10/1
期刊
JAMA ophthalmology
卷号
141
期号
10
页码范围
956-964
出版商
American Medical Association
简介
Importance
Calcium channel blocker (CCB) use has been associated with an increased risk of glaucoma in exploratory studies.
Objective
To examine the association of systemic CCB use with glaucoma and related traits among UK Biobank participants.
Design, Setting, and Participants
This population-based cross-sectional study included UK Biobank participants with complete data (2006-2010) for analysis of glaucoma status, intraocular pressure (IOP), and optical coherence tomography (OCT)–derived inner retinal layer thicknesses. Data analysis was conducted in January 2023.
Exposure
Calcium channel blocker use was assessed in a baseline touchscreen questionnaire and confirmed during an interview led by a trained nurse.
Main Outcomes and Measures
The primary outcome measures included glaucoma status, corneal-compensated IOP, and 2 OCT-derived inner retinal thickness parameters (macular retinal …
学术搜索中的文章
Calcium channel blocker use and associated glaucoma and related traits among UK biobank participants
A Kastner, KV Stuart, G Montesano, CG De Moraes… - JAMA ophthalmology, 2023