作者
Anthony P Khawaja, Sharon Chua, Pirro G Hysi, Stelios Georgoulas, Hannah Currant, Tomas W Fitzgerald, Ewan Birney, Fang Ko, Qi Yang, Charles Reisman, David F Garway-Heath, Chris J Hammond, Peng T Khaw, Paul J Foster, Praveen J Patel, Nicholas Strouthidis, Denize Atan, Tariq Aslam, Sarah A Barman, Jenny H Barrett, Paul Bishop, Peter Blows, Catey Bunce, Roxana O Carare, Usha Chakravarthy, Michelle Chan, Sharon YL Chua, David P Crabb, Philippa M Cumberland, Alexander Day, Parul Desai, Bal Dhillon, Andrew D Dick, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John EJ Gallacher, Jane Gibson, Dan Gore, Jeremy A Guggenheim, Alison Hardcastle, Simon P Harding, Ruth E Hogg, Pirro Hysi, Pearse A Keane, Gerassimos Lascaratos, Andrew J Lotery, Tom Macgillivray, Sarah Mackie, Keith Martin, Michelle McGaughey, Bernadette McGuinness, Gareth J McKay, Martin McKibbin, Danny Mitry, Tony Moore, James E Morgan, Zaynah A Muthy, Eoin O’Sullivan, Chris G Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Jugnoo S Rahi, Alicja R Rudnikca, Jay Self, Sobha Sivaprasad, David Steel, Irene Stratton, Cathie Sudlow, Dhanes Thomas, Emanuele Trucco, Adnan Tufail, Veronique Vitart, Stephen A Vernon, Ananth C Viswanathan, Cathy Williams, Katie Williams, Jayne V Woodside, Max M Yates, Jennifer Yip, Yalin Zheng
发表日期
2020/1/1
期刊
Ophthalmology
卷号
127
期号
1
页码范围
62-71
出版商
Elsevier
简介
Purpose
To describe and compare associations with macular retinal nerve fiber layer (mRNFL), ganglion cell complex (GCC), and ganglion cell–inner plexiform layer (GCIPL) thicknesses in a large cohort.
Design
Cross-sectional study.
Participants
We included 42 044 participants in the UK Biobank. The mean age was 56 years.
Methods
Spectral-domain OCT macular images were segmented and analyzed. Corneal-compensated intraocular pressure (IOPcc) was measured with the Ocular Response Analyzer (Reichert, Corp., Buffalo, NY). Multivariable linear regression was used to examine associations with mean mRNFL, GCC, and GCIPL thicknesses. Factors examined were age, sex, ethnicity, height, body mass index (BMI), smoking status, alcohol intake, Townsend deprivation index, education level, diabetes status, spherical equivalent, and IOPcc.
Main Outcome Measures
Thicknesses of mRNFL, GCC, and …
引用总数
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